The 49ers have gotten used to being shorthanded at running back this season and it looks like they’ll be down another one in Miami on Sunday.
Adam Schefter of ESPN reports that Isaac Guerendo is unlikely to play against the Dolphins. Guerendo did not practice on Wednesday after suffering a foot injury in Week 14 and hurting his hamstring last Sunday.
Guerendo was the lead back in the wake of the season-ending injuries suffered by Christian McCaffrey and Jordan Mason in recent weeks. He ran 31 times for 135 yards and two touchdowns and caught six passes for 68 yards in his two starts.
Patrick Taylor and Israel Abanikanda are the other backs on the 53-man roster. They also have Ke’Shawn Vaughn on the practice squad.