They round off the campaign against Japan on 11 October, with Scotland and South Africa also featuring in their pool.
There are nine changes from the Spain victory, with second row Gwen Crabb returning after injury and Jasmine Joyce-Butchers back in the Wales side having represented Great Britain Sevens at a third Olympic Games over the summer.
“It’s the start of a new season and we know we need to expose more players to the demands and intensity of Test match rugby,” added Cunningham.
“As coaches and staff, we know we need to build the squad’s depth and need competition for places.
“We have given some new players who have impressed in training and in the Under-20s Six Nations an opportunity to show what they can do at the highest level.”
Wales: Jenny Hesketh; Catherine Richards, Meg Webb, Kerin Lake, Jasmine Joyce; Robyn Wilkins, Keira Bevan (capt); Gwenllian Pyrs, Molly Reardon, Sisilia Tuipulotu, Natalia John, Gwen Crabb, Kate Williams, Bethan Lewis, Gwennan Hopkins.
Replacements: Rosie Carr, Maisie Davies, Donna Rose Alaw Pyrs, Alisha Butchers, Sian Jones, Lleucu George, Nel Metcalfe.